Bevacizumab dosing strategy in paediatric cancer patients based on population pharmacokinetic analysis with external validation

AIM: The aim of the present study was to evaluate the pharmacokinetics of bevacizumab and various dosing strategies for this agent in paediatric patients. METHODS: Data were collected from 232 paediatric patients (1971 concentrations) in five studies, with a wide range of age (0.5 – 21 years), body...

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Detalles Bibliográficos
Autores principales: Han, Kelong, Peyret, Thomas, Quartino, Angelica, Gosselin, Nathalie H., Gururangan, Sridharan, Casanova, Michela, Merks, Johannes H. M., Massimino, Maura, Grill, Jacques, Daw, Najat C., Navid, Fariba, Jin, Jin, Allison, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Paediatric Clinical Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693565/
https://www.ncbi.nlm.nih.gov/pubmed/26345283
http://dx.doi.org/10.1111/bcp.12778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693565/
https://www.ncbi.nlm.nih.gov/pubmed/26345283
http://dx.doi.org/10.1111/bcp.12778

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