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TNF and regulatory T cells are critical for sepsis‐induced suppression of T cells

The immune system in sepsis is impaired as seen by reduced numbers and function of immune cells and impaired antigen‐specific antibody responses. We studied T cell function in septic mice using cecal ligation and puncture (CLP) as a clinically relevant mouse model for sepsis. The proliferative respo...

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Detalles Bibliográficos
Autores principales: Stieglitz, David, Schmid, Tobias, Chhabra, Nirav F., Echtenacher, Bernd, Männel, Daniela N., Mostböck, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693718/
https://www.ncbi.nlm.nih.gov/pubmed/26734459
http://dx.doi.org/10.1002/iid3.75