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Parasite-Specific CD4(+) IFN-γ(+) IL-10(+) T Cells Distribute within Both Lymphoid and Nonlymphoid Compartments and Are Controlled Systemically by Interleukin-27 and ICOS during Blood-Stage Malaria Infection
Immune-mediated pathology in interleukin-10 (IL-10)-deficient mice during blood-stage malaria infection typically manifests in nonlymphoid organs, such as the liver and lung. Thus, it is critical to define the cellular sources of IL-10 in these sensitive nonlymphoid compartments during infection. Mo...
Autores principales: | Villegas-Mendez, Ana, Shaw, Tovah N., Inkson, Colette A., Strangward, Patrick, de Souza, J. Brian, Couper, Kevin N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693994/ https://www.ncbi.nlm.nih.gov/pubmed/26459508 http://dx.doi.org/10.1128/IAI.01100-15 |
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