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A comprehensive multiomics approach toward understanding the relationship between aging and dementia

Because age is the greatest risk factor for sporadic Alzheimer's disease (AD), phenotypic screens based upon old age-associated brain toxicities were used to develop the potent neurotrophic drug J147. Since certain aspects of aging may be primary cause of AD, we hypothesized that J147 would be...

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Detalles Bibliográficos
Autores principales: Currais, Antonio, Goldberg, Joshua, Farrokhi, Catherine, Chang, Max, Prior, Marguerite, Dargusch, Richard, Daugherty, Daniel, Armando, Aaron, Quehenberger, Oswald, Maher, Pamela, Schubert, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694064/
https://www.ncbi.nlm.nih.gov/pubmed/26564964