MEK inhibitors and their potential in the treatment of advanced melanoma: the advantages of combination therapy

The treatment of melanoma has improved markedly over the last several years with the advent of more targeted therapies. Unfortunately, complex compensation mechanisms, such as those of the mitogen-activated protein kinase (MAPK) pathway, have limited the clinical benefit of these treatments. Recentl...

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Detalles Bibliográficos
Autores principales: Tran, Khiem A, Cheng, Michelle Y, Mitra, Anupam, Ogawa, Hiromi, Shi, Vivian Y, Olney, Laura P, Kloxin, April M, Maverakis, Emanual
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694671/
https://www.ncbi.nlm.nih.gov/pubmed/26730180
http://dx.doi.org/10.2147/DDDT.S93545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694671/
https://www.ncbi.nlm.nih.gov/pubmed/26730180
http://dx.doi.org/10.2147/DDDT.S93545

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