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MEK inhibitors and their potential in the treatment of advanced melanoma: the advantages of combination therapy
The treatment of melanoma has improved markedly over the last several years with the advent of more targeted therapies. Unfortunately, complex compensation mechanisms, such as those of the mitogen-activated protein kinase (MAPK) pathway, have limited the clinical benefit of these treatments. Recentl...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694671/ https://www.ncbi.nlm.nih.gov/pubmed/26730180 http://dx.doi.org/10.2147/DDDT.S93545 |