Cargando…
Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature
BACKGROUND: Small GTPase Rap1 has been implicated in a number of basic cellular functions, including cell-cell and cell-matrix adhesion, proliferation and regulation of polarity. Evolutionarily conserved, Rap1 has been studied in model organisms: yeast, Drosophila and mice. Mouse in vivo studies imp...
Autores principales: | Chrzanowska-Wodnicka, Magdalena, White, Gilbert C., Quilliam, Lawrence A., Whitehead, Kevin J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694701/ https://www.ncbi.nlm.nih.gov/pubmed/26714318 http://dx.doi.org/10.1371/journal.pone.0145689 |
Ejemplares similares
-
Rap1 GTPase Activation and Barrier Enhancement in RPE Inhibits Choroidal Neovascularization In Vivo
por: Wittchen, Erika S., et al.
Publicado: (2013) -
Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes
por: Awasthi, Aradhana, et al.
Publicado: (2010) -
The small GTPase Rap1b negatively regulates neutrophil chemotaxis and transcellular diapedesis by inhibiting Akt activation
por: Kumar, Sachin, et al.
Publicado: (2014) -
Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization
por: Wang, Haibo, et al.
Publicado: (2016) -
Integration of Rap1 and Calcium Signaling
por: Kosuru, Ramoji, et al.
Publicado: (2020)