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Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature

BACKGROUND: Small GTPase Rap1 has been implicated in a number of basic cellular functions, including cell-cell and cell-matrix adhesion, proliferation and regulation of polarity. Evolutionarily conserved, Rap1 has been studied in model organisms: yeast, Drosophila and mice. Mouse in vivo studies imp...

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Detalles Bibliográficos
Autores principales: Chrzanowska-Wodnicka, Magdalena, White, Gilbert C., Quilliam, Lawrence A., Whitehead, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694701/
https://www.ncbi.nlm.nih.gov/pubmed/26714318
http://dx.doi.org/10.1371/journal.pone.0145689

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