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Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death

The B-cell lymphoma-2 (Bcl-2) family proteins are critical regulators of apoptosis and consist of both proapoptotic and antiapoptotic factors. Within this family, the myeloid cell leukemia factor 1 (Mcl-1) protein exists in two forms as the result of alternative splicing. The long variant (Mcl-1L) a...

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Detalles Bibliográficos
Autores principales: Morciano, Giampaolo, Giorgi, Carlotta, Balestra, Dario, Marchi, Saverio, Perrone, Daniela, Pinotti, Mirko, Pinton, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694758/
https://www.ncbi.nlm.nih.gov/pubmed/26538029
http://dx.doi.org/10.1091/mbc.E15-01-0028