Ccdc11 is a novel centriolar satellite protein essential for ciliogenesis and establishment of left–right asymmetry

The establishment of left–right (L-R) asymmetry in vertebrates is dependent on the sensory and motile functions of cilia during embryogenesis. Mutations in CCDC11 disrupt L-R asymmetry and cause congenital heart disease in humans, yet the molecular and cellular functions of the protein remain unknow...

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Detalles Bibliográficos
Autores principales: Silva, Erica, Betleja, Ewelina, John, Emily, Spear, Philip, Moresco, James J., Zhang, Siwei, Yates, John R., Mitchell, Brian J., Mahjoub, Moe R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694761/
https://www.ncbi.nlm.nih.gov/pubmed/26538025
http://dx.doi.org/10.1091/mbc.E15-07-0474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694761/
https://www.ncbi.nlm.nih.gov/pubmed/26538025
http://dx.doi.org/10.1091/mbc.E15-07-0474

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