Cargando…
Ccdc11 is a novel centriolar satellite protein essential for ciliogenesis and establishment of left–right asymmetry
The establishment of left–right (L-R) asymmetry in vertebrates is dependent on the sensory and motile functions of cilia during embryogenesis. Mutations in CCDC11 disrupt L-R asymmetry and cause congenital heart disease in humans, yet the molecular and cellular functions of the protein remain unknow...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694761/ https://www.ncbi.nlm.nih.gov/pubmed/26538025 http://dx.doi.org/10.1091/mbc.E15-07-0474 |