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Modeling-Enabled Characterization of Novel NLRX1 Ligands
Nucleotide-binding domain and leucine-rich repeat containing (NLR) family are intracellular sentinels of cytosolic homeostasis that orchestrate immune and inflammatory responses in infectious and immune-mediated diseases. NLRX1 is a mitochondrial-associated NOD-like receptor involved in the modulati...
Autores principales: | Lu, Pinyi, Hontecillas, Raquel, Abedi, Vida, Kale, Shiv, Leber, Andrew, Heltzel, Chase, Langowski, Mark, Godfrey, Victoria, Philipson, Casandra, Tubau-Juni, Nuria, Carbo, Adria, Girardin, Stephen, Uren, Aykut, Bassaganya-Riera, Josep |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694766/ https://www.ncbi.nlm.nih.gov/pubmed/26714018 http://dx.doi.org/10.1371/journal.pone.0145420 |
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