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Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models
Triple negative, resistant or metastatic disease are major factors in breast cancer mortality, warranting novel approaches. Carbonic anhydrase IX (CAIX) is implicated in survival, migration and invasion of breast cancer cells and inhibition provides an innovative therapeutic strategy. The efficacy o...
Autores principales: | Ward, Carol, Meehan, James, Mullen, Peter, Supuran, Claudiu, Dixon, J. Michael, Thomas, Jeremy S., Winum, Jean-Yves, Lambin, Philippe, Dubois, Ludwig, Pavathaneni, Nanda-Kumar, Jarman, Edward J., Renshaw, Lorna, Um, InHwa, Kay, Charlene, Harrison, David J., Kunkler, Ian H., Langdon, Simon P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694798/ https://www.ncbi.nlm.nih.gov/pubmed/26259239 |
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