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A measles virus selectively blind to signaling lymphocytic activation molecule shows anti-tumor activity against lung cancer cells
Lung cancer cells, particularly those of non-small-cell lung cancer, are known to express Nectin-4. We previously generated a recombinant measles virus that uses Nectin-4 as its receptor but cannot bind its original principal receptor, signaling lymphocyte activation molecule (SLAM). This virus (rMV...
Autores principales: | Fujiyuki, Tomoko, Yoneda, Misako, Amagai, Yosuke, Obayashi, Kunie, Ikeda, Fusako, Shoji, Koichiro, Murakami, Yoshinori, Sato, Hiroki, Kai, Chieko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694801/ https://www.ncbi.nlm.nih.gov/pubmed/26317644 |
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