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Glioblastoma invasion and cooption depend on IRE1α endoribonuclease activity

IRE1α is an endoplasmic reticulum (ER)-resident transmembrane signaling protein and a cellular stress sensor. The protein harbors a cytosolic dual kinase/endoribonuclease activity required for adaptive responses to micro-environmental changes. In an orthotopic xenograft model of human glioma, invali...

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Detalles Bibliográficos
Autores principales:	Jabouille, Arnaud, Delugin, Maylis, Pineau, Raphaël, Dubrac, Alexandre, Soulet, Fabienne, Lhomond, Stéphanie, Pallares-Lupon, Nestor, Prats, Hervé, Bikfalvi, Andreas, Chevet, Eric, Touriol, Christian, Moenner, Michel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694804/ https://www.ncbi.nlm.nih.gov/pubmed/26325176

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