Non genomic loss of function of tumor suppressors in CML: BCR-ABL promotes IκBα mediated p53 nuclear exclusion

Tumor suppressor function can be modulated by subtle variation of expression levels, proper cellular compartmentalization and post-translational modifications, such as phosphorylation, acetylation and sumoylation. The non-genomic loss of function of tumor suppressors offers a challenging therapeutic...

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Detalles Bibliográficos
Autores principales: Crivellaro, Sabrina, Panuzzo, Cristina, Carrà, Giovanna, Volpengo, Alessandro, Crasto, Francesca, Gottardi, Enrico, Familiari, Ubaldo, Papotti, Mauro, Torti, Davide, Piazza, Rocco, Redaelli, Sara, Taulli, Riccardo, Guerrasio, Angelo, Saglio, Giuseppe, Morotti, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694826/
https://www.ncbi.nlm.nih.gov/pubmed/26295305

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