RY-2f, an isoflavone analog, overcomes cisplatin resistance to inhibit ovarian tumorigenesis via targeting the PI3K/AKT/mTOR signaling pathway

Ovarian cancer remains the leading cause of death in gynecologic malignancies partially because of resistance to chemotherapy. In the present study, we show that RY-2f, a chemically synthesized isoflavone analog, inhibited ovarian cancer cell proliferation, blocked cell cycle in G2/M phase and induc...

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Detalles Bibliográficos
Autores principales: Liu, Mingming, Qi, Zihao, Liu, Bingzhi, Ren, Yi, Li, Hanbin, Yang, Gong, Zhang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694831/
https://www.ncbi.nlm.nih.gov/pubmed/26325371

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