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Calmodulin antagonists promote TRA-8 therapy of resistant pancreatic cancer

Pancreatic cancer is highly malignant with limited therapy and a poor prognosis. TRAIL-activating therapy has been promising, however, clinical trials have shown resistance and limited responses of pancreatic cancers. We investigated the effects of calmodulin(CaM) antagonists, trifluoperazine(TFP) a...

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Detalles Bibliográficos
Autores principales: Yuan, Kaiyu, Yong, Sun, Xu, Fei, Zhou, Tong, McDonald, Jay M, Chen, Yabing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694833/
https://www.ncbi.nlm.nih.gov/pubmed/26320171