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NF-κB/RelA-PKM2 mediates inhibition of glycolysis by fenofibrate in glioblastoma cells

Aerobic glycolysis (production of lactate from glucose in the presence of oxygen) is a hallmark of cancer. Fenofibrate is a lipid-lowering drug and an agonist of the peroxisome proliferator-activated receptor alpha (PPARα). We found that FF inhibited glycolysis in a PPARα-dependent manner in gliobla...

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Detalles Bibliográficos
Autores principales:	Han, Dongfeng, Wei, Wenjin, Chen, Xincheng, Zhang, Yaxuan, Wang, Yingyi, Zhang, Junxia, Wang, Xiefeng, Yu, Tianfu, Hu, Qi, Liu, Ning, You, Yongping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694890/ https://www.ncbi.nlm.nih.gov/pubmed/26172294

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