Small molecule inhibitors of Late SV40 Factor (LSF) abrogate hepatocellular carcinoma (HCC): Evaluation using an endogenous HCC model

Hepatocellular carcinoma (HCC) is a lethal malignancy with high mortality and poor prognosis. Oncogenic transcription factor Late SV40 Factor (LSF) plays an important role in promoting HCC. A small molecule inhibitor of LSF, Factor Quinolinone Inhibitor 1 (FQI1), significantly inhibited human HCC xe...

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Detalles Bibliográficos
Autores principales: Rajasekaran, Devaraja, Siddiq, Ayesha, Willoughby, Jennifer L.S., Biagi, Jessica M., Christadore, Lisa M., Yunes, Sarah A., Gredler, Rachel, Jariwala, Nidhi, Robertson, Chadia L., Akiel, Maaged A., Shen, Xue-Ning, Subler, Mark A., Windle, Jolene J., Schaus, Scott E., Fisher, Paul B., Hansen, Ulla, Sarkar, Devanand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694900/
https://www.ncbi.nlm.nih.gov/pubmed/26313006

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