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IKK inhibition increases bortezomib effectiveness in ovarian cancer
Ovarian cancer is associated with increased expression of the pro-angiogenic chemokine interleukin-8 (IL-8, CXCL8), which induces tumor cell proliferation, angiogenesis, and metastasis. Even though bortezomib (BZ) has shown remarkable anti-tumor activity in hematological malignancies, it has been le...
Autores principales: | Singha, Bipradeb, Gatla, Himavanth Reddy, Phyo, Sai, Patel, Atish, Chen, Zhe-Sheng, Vancurova, Ivana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694906/ https://www.ncbi.nlm.nih.gov/pubmed/26267322 |
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