Genomic amplification of 9p24.1 targeting JAK2, PD-L1, and PD-L2 is enriched in high-risk triple negative breast cancer

We used DNA content flow cytometry followed by oligonucleotide array based comparative genomic hybridization to survey the genomes of 326 tumors, including 41 untreated surgically resected triple negative breast cancers (TNBC). A high level (log(2)ratio ≥1) 9p24 amplicon was found in TNBC (12/41), g...

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Detalles Bibliográficos
Autores principales: Barrett, Michael T., Anderson, Karen S., Lenkiewicz, Elizabeth, Andreozzi, Mariacarla, Cunliffe, Heather E., Klassen, Christine L., Dueck, Amylou C., McCullough, Ann E., Reddy, Srikanth K., Ramanathan, Ramesh K., Northfelt, Donald W., Pockaj, Barbara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694916/
https://www.ncbi.nlm.nih.gov/pubmed/26317899

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