DNA double strand break repair defect and sensitivity to poly ADP-ribose polymerase (PARP) inhibition in human papillomavirus 16-positive head and neck squamous cell carcinoma

Patients with human papillomavirus-positive (HPV+) head and neck squamous cell carcinomas (HNSCCs) have increased response to radio- and chemotherapy and improved overall survival, possibly due to an impaired DNA damage response. Here, we investigated the correlation between HPV status and repair of...

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Detalles Bibliográficos
Autores principales: Weaver, Alice N., Cooper, Tiffiny S., Rodriguez, Marcela, Trummell, Hoa Q., Bonner, James A., Rosenthal, Eben L., Yang, Eddy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694969/
https://www.ncbi.nlm.nih.gov/pubmed/26336991

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