By inhibiting Ras/Raf/ERK and MMP-9, knockdown of EpCAM inhibits breast cancer cell growth and metastasis

Epithelial cell adhesion molecule (EpCAM) is a type I transmembrane protein that is expressed in the majority of normal epithelial tissues and is overexpressed in most epithelial cancers including breast cancer, where it plays an important role in cancer progression. However, the mechanism by which...

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Detalles Bibliográficos
Autores principales: Gao, Jiujiao, Liu, Xue, Yang, Fan, Liu, Tingjiao, Yan, Qiu, Yang, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694982/
https://www.ncbi.nlm.nih.gov/pubmed/26356670

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