STAT3 pathway regulates lung-derived brain metastasis initiating cell capacity through miR-21 activation

Brain metastases (BM) represent the most common tumor to affect the adult central nervous system. Despite the increasing incidence of BM, likely due to consistently improving treatment of primary cancers, BM remain severely understudied. In this study, we utilized patient-derived stem cell lines fro...

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Detalles Bibliográficos
Autores principales: Singh, Mohini, Garg, Neha, Venugopal, Chitra, Hallett, Robin, Tokar, Tomas, McFarlane, Nicole, Mahendram, Sujeivan, Bakhshinyan, David, Manoranjan, Branavan, Vora, Parvez, Qazi, Maleeha, Arpin, Carolynn C., Page, Brent, Haftchenary, Sina, Rosa, David A., Lai, Ping-Shan, Gómez-Biagi, Rodolfo F., Ali, Ahmed M., Lewis, Andrew, Geletu, Mulu, Murty, Naresh K., Hassell, John A., Jurisica, Igor, Gunning, Patrick T., Singh, Sheila K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695002/
https://www.ncbi.nlm.nih.gov/pubmed/26314961

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