Inhibition of poly(ADP-ribose) polymerase 1 protects against acute myeloid leukemia by suppressing the myeloproliferative leukemia virus oncogene

An abnormal expression of poly(ADP-ribose) polymerase 1 (PARP-1) has been described in many tumors. PARP-1 promotes tumorigenesis and cancer progression by acting on different molecular pathways. PARP-1 inhibitors can be used with radiotherapy or chemotherapy to enhance the susceptibility of tumor c...

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Detalles Bibliográficos
Autores principales: Wang, Lingbo, Cai, Weili, Zhang, Wei, Chen, Xueying, Dong, Wenqian, Tang, Dongqi, Zhang, Yun, Ji, Chunyan, Zhang, Mingxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695004/
https://www.ncbi.nlm.nih.gov/pubmed/26314963

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