Repositioning antipsychotic chlorpromazine for treating colorectal cancer by inhibiting sirtuin 1

Investigating existing drugs for repositioning can enable overcoming bottlenecks in the drug development process. Here, we investigated the effect and molecular mechanism of the antipsychotic drug chlorpromazine (CPZ) and identified its potential for treating colorectal cancer (CRC). Human CRC cell...

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Detalles Bibliográficos
Autores principales: Lee, Wen-Ying, Lee, Wai-Theng, Cheng, Chia-Hsiung, Chen, Ku-Chung, Chou, Chih-Ming, Chung, Chu-Hung, Sun, Min-Siou, Cheng, Hung-Wei, Ho, Meng-Ni, Lin, Cheng-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695010/
https://www.ncbi.nlm.nih.gov/pubmed/26363315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695010/
https://www.ncbi.nlm.nih.gov/pubmed/26363315

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