A new phosphorylated form of Ku70 identified in resistant leukemic cells confers fast but unfaithful dna repair in cancer cell lines

Ku70-dependent canonical nonhomologous end-joining (c-NHEJ) DNA repair system is fundamental to the genome maintenance and B-cell lineage. c-NHEJ is upregulated and error-prone in incurable forms of chronic lymphocytic leukemia which also displays telomere dysfunction, multiple chromosomal aberratio...

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Detalles Bibliográficos
Autores principales: Bouley, Julien, Saad, Lina, Grall, Romain, Schellenbauer, Amelie, Biard, Denis, Paget, Vincent, Morel-Altmeyer, Sandrine, Guipaud, Olivier, Chambon, Christophe, Salles, Bernard, Maloum, Karim, Merle-Béral, Hélène, Chevillard, Sylvie, Delic, Jozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695039/
https://www.ncbi.nlm.nih.gov/pubmed/26337656

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