Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

Hepatocellular carcinoma (HCC) is characterized by the accumulation of unfolded proteins in the endoplasmic reticulum (ER), which activates the unfolded protein response (UPR). However, the role of ER stress in tumor initiation and progression is controversial. To determine the impact of ER stress,...

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Detalles Bibliográficos
Autores principales: Vandewynckel, Yves-Paul, Laukens, Debby, Devisscher, Lindsey, Paridaens, Annelies, Bogaerts, Eliene, Verhelst, Xavier, Van den Bussche, Anja, Raevens, Sarah, Van Steenkiste, Christophe, Van Troys, Marleen, Ampe, Christophe, Descamps, Benedicte, Vanhove, Chris, Govaere, Olivier, Geerts, Anja, Van Vlierberghe, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695041/
https://www.ncbi.nlm.nih.gov/pubmed/26293671

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