V-ATPase: a master effector of E2F1-mediated lysosomal trafficking, mTORC1 activation and autophagy

In addition to being a master regulator of cell cycle progression, E2F1 regulates other associated biological processes, including growth and malignancy. Here, we uncover a regulatory network linking E2F1 to lysosomal trafficking and mTORC1 signaling that involves v-ATPase regulation. By immunofluor...

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Detalles Bibliográficos
Autores principales: Meo-Evoli, Nathalie, Almacellas, Eugènia, Massucci, Francesco Alessandro, Gentilella, Antonio, Ambrosio, Santiago, Kozma, Sara C., Thomas, George, Tauler, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695044/
https://www.ncbi.nlm.nih.gov/pubmed/26356814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695044/
https://www.ncbi.nlm.nih.gov/pubmed/26356814

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