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HIF isoforms have divergent effects on invasion, metastasis, metabolism and formation of lipid droplets

Cancer cells adapt to hypoxia by the stabilization of hypoxia inducible factor (HIF)-α isoforms that increase the transcription of several genes. Among the genes regulated by HIF are enzymes that play a role in invasion, metastasis and metabolism. We engineered triple (estrogen receptor/progesterone...

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Detalles Bibliográficos
Autores principales: Shah, Tariq, Krishnamachary, Balaji, Wildes, Flonne, Mironchik, Yelena, Kakkad, Samata M., Jacob, Desmond, Artemov, Dmitri, Bhujwalla, Zaver M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695047/
https://www.ncbi.nlm.nih.gov/pubmed/26305551

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