WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene

The Kruppel-like protein ZNF224 is a co-factor of the Wilms’ tumor 1 protein, WT1. We have previously shown that ZNF224 exerts a specific proapoptotic role in chronic myelogenous leukemia (CML) K562 cells and contributes to cytosine arabinoside-induced apoptosis, by modulating WT1-dependent transcri...

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Detalles Bibliográficos
Autores principales: Montano, Giorgia, Vidovic, Karina, Palladino, Chiara, Cesaro, Elena, Sodaro, Gaetano, Quintarelli, Concetta, De Angelis, Biagio, Errichiello, Santa, Pane, Fabrizio, Izzo, Paola, Grosso, Michela, Gullberg, Urban, Costanzo, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695056/
https://www.ncbi.nlm.nih.gov/pubmed/26320177

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