Addiction of pancreatic cancer cells to zinc-finger transcription factor ZIC2

Activity of GLI transcription factors of Hedgehog signaling is key for various cancer cell properties, especially in pancreatic ductal adenocarcinoma (PDAC). Zinc-finger transcriptional regulators ZIC1 to ZIC5 of ZIC gene family were demonstrated to associate with GLI to increase the nuclear accumul...

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Detalles Bibliográficos
Autores principales: Inaguma, Shingo, Ito, Hideaki, Riku, Miho, Ikeda, Hiroshi, Kasai, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695058/
https://www.ncbi.nlm.nih.gov/pubmed/26318045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695058/
https://www.ncbi.nlm.nih.gov/pubmed/26318045

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