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Addiction of pancreatic cancer cells to zinc-finger transcription factor ZIC2
Activity of GLI transcription factors of Hedgehog signaling is key for various cancer cell properties, especially in pancreatic ductal adenocarcinoma (PDAC). Zinc-finger transcriptional regulators ZIC1 to ZIC5 of ZIC gene family were demonstrated to associate with GLI to increase the nuclear accumul...
Autores principales: | Inaguma, Shingo, Ito, Hideaki, Riku, Miho, Ikeda, Hiroshi, Kasai, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695058/ https://www.ncbi.nlm.nih.gov/pubmed/26318045 |
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