Cargando…

Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells

Melanoma is the most deadly form of cutaneous malignancy, and its incidence rates are rising worldwide. In melanoma, constitutive activation of the BRAF/MEK/ERK (MAPK) and PI3K/AKT/mTOR (PI3K) signaling pathways plays a pivotal role in cell proliferation, survival and tumorigenesis. A combination of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pal, Harish Chandra, Baxter, Ronald D., Hunt, Katherine M., Agarwal, Jyoti, Elmets, Craig A., Athar, Mohammad, Afaq, Farrukh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695061/ https://www.ncbi.nlm.nih.gov/pubmed/26299806

Ejemplares similares

Fisetin, a dietary flavonoid, augments the anti-invasive and anti-metastatic potential of sorafenib in melanoma
por: Pal, Harish C., et al.
Publicado: (2015)

Fisetin Inhibits Human Melanoma Cell Invasion through Promotion of Mesenchymal to Epithelial Transition and by Targeting MAPK and NFκB Signaling Pathways
por: Pal, Harish Chandra, et al.
Publicado: (2014)

Delphinidin Reduces Cell Proliferation and Induces Apoptosis of Non-Small-Cell Lung Cancer Cells by Targeting EGFR/VEGFR2 Signaling Pathways
por: Pal, Harish Chandra, et al.
Publicado: (2013)

Study of Camelpox Virus Pathogenesis in Athymic Nude Mice
por: Duraffour, Sophie, et al.
Publicado: (2011)

Growth of human digestive-tumour xenografts in athymic nude rats.
por: Davies, G., et al.
Publicado: (1981)

BCG treatment of human tumour xenografts in athymic nude mice.
por: Pimm, M. V., et al.
Publicado: (1978)

C. parvum suppression of rat tumours in athymic nude mice.
por: Pimm, M. V., et al.
Publicado: (1976)

Vascularity and perfusion of human gliomas xenografted in the athymic nude mouse.
por: Bernsen, H. J., et al.
Publicado: (1995)

Cellular requirements for renal allograft rejection in the athymic nude rat
Publicado: (1989)

Characterization of locomotor activity circadian rhythms in athymic nude mice
por: Paladino, Natalia, et al.
Publicado: (2013)

Serological aspects of rat tumour xenograft growth in athymic nude mice.
por: Pimm, M. V., et al.
Publicado: (1979)

T-cell lymphoma induction by radiation leukemia virus in athymic nude mice
Publicado: (1978)

Influence of tumour size on human prostate tumour metastasis in athymic nude mice.
por: Ware, J. L., et al.
Publicado: (1985)

Vascular structure of five human malignant melanomas grown in athymic nude mice.
por: Solesvik, O. V., et al.
Publicado: (1982)

Mechanism of rejection of virus persistently infected tumor cells by athymic nude mice
Publicado: (1979)

Defining cutaneous molecular pathobiology of arsenicals using phenylarsine oxide as a prototype
por: Srivastava, Ritesh K., et al.
Publicado: (2016)

MAINTENANCE OF SKIN XENOGRAFTS OF WIDELY DIVERGENT PHYLOGENETIC ORIGIN ON CONGENITALLY ATHYMIC (NUDE) MICE
por: Manning, Dean D., et al.
Publicado: (1973)

Chrysin Induces Antidiabetic, Antidyslipidemic and Anti-Inflammatory Effects in Athymic Nude Diabetic Mice
por: Ramírez-Espinosa, Juan José, et al.
Publicado: (2017)

Vascularization and innervation of slits within polydimethylsiloxane sheets in the subcutaneous space of athymic nude mice
por: Gurlin, Rachel E, et al.
Publicado: (2017)

Induction and abrogation of unresponsiveness in nude mouse cells
Publicado: (1976)

Antiproliferative effect of methyl-beta-cyclodextrin in vitro and in human tumour xenografted athymic nude mice.
por: Grosse, P. Y., et al.
Publicado: (1998)

Phellinus Linteus Extract Sensitizes Advanced Prostate Cancer Cells to Apoptosis in Athymic Nude Mice
por: Tsuji, Takanori, et al.
Publicado: (2010)

Dietary Stearic Acid Leads to a Reduction of Visceral Adipose Tissue in Athymic Nude Mice
por: Shen, Ming-Che, et al.
Publicado: (2014)

Gut Microbiota Shifts in Pup Athymic BALB/c Mice: An Updated Identification in Nude Mice
por: Li, Yuting, et al.
Publicado: (2019)

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
por: Trombone, Ana Paula Fávaro, et al.
Publicado: (2014)

Detection of Corynebacterium bovis infection in athymic nude mice from a research animal facility in Korea
por: Kim, Tae-Hyoun, et al.
Publicado: (2014)

Alterations of Mouse Proto‐oncogenes in Sarcomas Induced after Transplantation of Human Tumors in Athymic Nude Mice
por: Yuasa, Yasuhito, et al.
Publicado: (1990)

Evaluation of Anti-Tumorigenic Effects of Diosmetin against Human Colon Cancer Xenografts in Athymic Nude Mice
por: Koosha, Sanaz, et al.
Publicado: (2019)

Interferon gamma is involved in the recovery of athymic nude mice from recombinant vaccinia virus/interleukin 2 infection
Publicado: (1990)

Fidelity of the repertoire in T cell reconstituted athymic nude rats. Preservation of a deficit in alloresponsiveness over one year
Publicado: (1989)

Tumor Grafting Induces Changes of Gut Microbiota in Athymic Nude Mice in the Presence and Absence of Medicinal Gynostemma Saponins
por: Chen, Lei, et al.
Publicado: (2015)

Light enhanced bone regeneration in an athymic nude mouse implanted with mesenchymal stem cells embedded in PLGA microspheres
por: Park, Ji Sun, et al.
Publicado: (2016)

NSG Mice Provide a Better Spontaneous Model of Breast Cancer Metastasis than Athymic (Nude) Mice
por: Puchalapalli, Madhavi, et al.
Publicado: (2016)

Congenitally athymic nude (nu/nu) mice have Thy-1-bearing immunocompetent helper T cells in their peritoneal cavity
Publicado: (1980)

Prominent IL-12 Production and Tumor Reduction in Athymic Nude Mice after Toxoplasma gondii Lysate Antigen Treatment
por: Pyo, Kyoung-Ho, et al.
Publicado: (2014)

Toxicological studies of Orthosiphon stamineus (Misai Kucing) standardized ethanol extract in combination with gemcitabine in athymic nude mice model
por: Yehya, Ashwaq H.S., et al.
Publicado: (2018)

Mouse thymic virus (MTLV; Murid Herpesvirus 3) infection in athymic nude mice: Evidence for a T lymphocyte requirement
por: Morse, Stephen S.
Publicado: (1988)

Inhibiting Cycloxygenase and Ornithine Decarboxylase by Diclofenac and Alpha-Difluoromethylornithine Blocks Cutaneous SCCs by Targeting Akt-ERK Axis
por: Arumugam, Aadithya, et al.
Publicado: (2013)

An Antioxidant, Probucol, Induces Anti‐angiogenesis and Apoptosis in Athymic Nude Mouse Xenografted Human Head and Neck Squamous Carcinoma Cells
por: Nishimura, Goshi, et al.
Publicado: (1999)

Cardamonin Exerts Antitumor Effect on Human Hepatocellular Carcinoma Xenografts in Athymic Nude Mice through Inhibiting NF-κβ Pathway
por: Badroon, Nassrin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8vne83ushmdljr6gkkfmsgtpke