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Tissue Restricted Splice Junctions Originate Not Only from Tissue-Specific Gene Loci, but Gene Loci with a Broad Pattern of Expression

Cellular mechanisms that achieve protein diversity in eukaryotes are multifaceted, including transcriptional components such as RNA splicing. Through alternative splicing, a single protein-coding gene can generate multiple mRNA transcripts and protein isoforms, some of which are tissue-specific. We...

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Detalles Bibliográficos
Autores principales: Hestand, Matthew S., Zeng, Zheng, Coleman, Stephen J., Liu, Jinze, MacLeod, James N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695084/
https://www.ncbi.nlm.nih.gov/pubmed/26713731
http://dx.doi.org/10.1371/journal.pone.0144302

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