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Tissue Restricted Splice Junctions Originate Not Only from Tissue-Specific Gene Loci, but Gene Loci with a Broad Pattern of Expression
Cellular mechanisms that achieve protein diversity in eukaryotes are multifaceted, including transcriptional components such as RNA splicing. Through alternative splicing, a single protein-coding gene can generate multiple mRNA transcripts and protein isoforms, some of which are tissue-specific. We...
Autores principales: | Hestand, Matthew S., Zeng, Zheng, Coleman, Stephen J., Liu, Jinze, MacLeod, James N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695084/ https://www.ncbi.nlm.nih.gov/pubmed/26713731 http://dx.doi.org/10.1371/journal.pone.0144302 |
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