Dual mTORC1/C2 inhibitors: gerosuppressors with potential anti-aging effect

Over the past decade, our understanding of the molecular and cellular mechanisms presiding over cellular and tissue decline with aging has greatly advanced. Classical hallmarks of aging cell include increasing levels of reactive oxygen species, DNA damage and senescence entry, which disrupt tissue a...

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Detalles Bibliográficos
Autores principales: Sousa-Victor, Pedro, García-Prat, Laura, Muñoz-Cánoves, Pura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695106/
https://www.ncbi.nlm.nih.gov/pubmed/26375366

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