Non-coding RNAs including miRNAs, piRNAs, and tRNAs in human cancer

Over 98% of our genes code for RNA transcripts that will never become translated into protein. Numerous non-coding RNA (ncRNA) transcripts are structurally and functionally diverse. In particular, micro RNAs (miRNAs), piwi-interacting RNAs (piRNAs), and, more recently, transfer RNAs (tRNAs) are impl...

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Autores principales: Heyns, Mieke, Kovalchuk, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695107/
https://www.ncbi.nlm.nih.gov/pubmed/26405161
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author Heyns, Mieke
Kovalchuk, Olga
author_facet Heyns, Mieke
Kovalchuk, Olga
author_sort Heyns, Mieke
collection PubMed
description Over 98% of our genes code for RNA transcripts that will never become translated into protein. Numerous non-coding RNA (ncRNA) transcripts are structurally and functionally diverse. In particular, micro RNAs (miRNAs), piwi-interacting RNAs (piRNAs), and, more recently, transfer RNAs (tRNAs) are implicated as regulators of key genes and processes that are involved in various human diseases, including cancer. Here, we summarize the recent findings and perspectives in the small RNA and cancer research.
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spelling pubmed-46951072016-01-26 Non-coding RNAs including miRNAs, piRNAs, and tRNAs in human cancer Heyns, Mieke Kovalchuk, Olga Oncotarget Research Perspective Over 98% of our genes code for RNA transcripts that will never become translated into protein. Numerous non-coding RNA (ncRNA) transcripts are structurally and functionally diverse. In particular, micro RNAs (miRNAs), piwi-interacting RNAs (piRNAs), and, more recently, transfer RNAs (tRNAs) are implicated as regulators of key genes and processes that are involved in various human diseases, including cancer. Here, we summarize the recent findings and perspectives in the small RNA and cancer research. Impact Journals LLC 2015-07-31 /pmc/articles/PMC4695107/ /pubmed/26405161 Text en Copyright: © 2015 Heyns and Kovalchuk http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Perspective
Heyns, Mieke
Kovalchuk, Olga
Non-coding RNAs including miRNAs, piRNAs, and tRNAs in human cancer
title Non-coding RNAs including miRNAs, piRNAs, and tRNAs in human cancer
title_full Non-coding RNAs including miRNAs, piRNAs, and tRNAs in human cancer
title_fullStr Non-coding RNAs including miRNAs, piRNAs, and tRNAs in human cancer
title_full_unstemmed Non-coding RNAs including miRNAs, piRNAs, and tRNAs in human cancer
title_short Non-coding RNAs including miRNAs, piRNAs, and tRNAs in human cancer
title_sort non-coding rnas including mirnas, pirnas, and trnas in human cancer
topic Research Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695107/
https://www.ncbi.nlm.nih.gov/pubmed/26405161
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