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p53-regulated autophagy is controlled by glycolysis and determines cell fate

The tumor suppressor p53 regulates downstream targets that determine cell fate. Canonical p53 functions include inducing apoptosis, growth arrest, and senescence. Non-canonical p53 functions include its ability to promote or inhibit autophagy and its ability to regulate metabolism. The extent to whi...

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Detalles Bibliográficos
Autores principales:	Duan, Lei, Perez, Ricardo E., Davaadelger, Batzaya, Dedkova, Elena N., Blatter, Lothar A., Maki, Carl G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Priority Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695109/ https://www.ncbi.nlm.nih.gov/pubmed/26337205

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