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The endoplasmic reticulum mitochondrial calcium cross talk is downregulated in malignant pleural mesothelioma cells and plays a critical role in apoptosis inhibition
The failure of apoptosis may contribute to the formation of cancer and to its resistance to therapy. Malignant pleural mesothelioma (MPM) is an aggressive tumor that responds poorly to standard chemo- and radio-therapies. Several studies have demonstrated that a plethora of oncogenes and tumor suppr...
Autores principales: | Patergnani, Simone, Giorgi, Carlotta, Maniero, Stefania, Missiroli, Sonia, Maniscalco, Pio, Bononi, Ilaria, Martini, Fernanda, Cavallesco, Giorgio, Tognon, Mauro, Pinton, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695128/ https://www.ncbi.nlm.nih.gov/pubmed/26156019 |
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