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Time-course gene profiling and networks in demethylated retinoblastoma cell line

Retinoblastoma, a very aggressive cancer of the developing retina, initiatiates by the biallelic loss of RB1 gene, and progresses very quickly following RB1 inactivation. While its genome is stable, multiple pathways are deregulated, also epigenetically. After reviewing the main findings in relation...

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Detalles Bibliográficos
Autores principales: Malusa, Federico, Taranta, Monia, Zaki, Nazar, Cinti, Caterina, Capobianco, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695145/
https://www.ncbi.nlm.nih.gov/pubmed/26143641