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Protein tyrosine phosphatase SHP2 promotes invadopodia formation through suppression of Rho signaling

Invadopodia are actin-enriched membrane protrusions that are important for extracellular matrix degradation and invasive cell motility. Src homolog domain-containing phosphatase 2 (SHP2), a non-receptor protein tyrosine phosphatase, has been shown to play an important role in promoting cancer metast...

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Detalles Bibliográficos
Autores principales:	Tsai, Wan-Chen, Chen, Chien-Lin, Chen, Hong-Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695156/ https://www.ncbi.nlm.nih.gov/pubmed/26204488

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