MicroRNA-7 inhibits the stemness of prostate cancer stem-like cells and tumorigenesis by repressing KLF4/PI3K/Akt/p21 pathway

Up to now, the molecular mechanisms underlying the stemness of prostate cancer stem cells (PCSCs) are still poorly understood. In this study, we demonstrated that microRNA-7 (miR-7) appears to be a novel tumor-suppressor miRNA, which abrogates the stemness of PCSCs and inhibits prostate tumorigenesi...

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Detalles Bibliográficos
Autores principales: Chang, Yun-Li, Zhou, Pei-Jie, Wei, Lianzi, Li, Wang, Ji, Zhongzhong, Fang, Yu-Xiang, Gao, Wei-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695167/
https://www.ncbi.nlm.nih.gov/pubmed/26172296

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