Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells

Doxorubicin (Doxo) is one of the most widely used chemotherapeutic drugs for patients with hepatocellular carcinoma (HCC). Doxo is a DNA intercalating drug that inhibits topoisomerase II. Thereby Doxo has the ability to block DNA replication and induce apoptosis. However, the other targets and mecha...

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Detalles Bibliográficos
Autores principales: Wang, Jiayi, Ma, Lifang, Tang, Xun, Zhang, Xiao, Qiao, Yongxia, Shi, Yuling, Xu, Yanfeng, Wang, Zhongyong, Yu, Yongchun, Sun, Fenyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695171/
https://www.ncbi.nlm.nih.gov/pubmed/26124182

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