Semi-synthetic ocotillol analogues as selective ABCB1-mediated drug resistance reversal agents

Overexpression of ATP-Binding Cassette transporters leads to multidrug resistance in cancer cells and results in the failure of chemotherapy. In this in-vitro study, we investigated whether or not (20S, 24R/S)-epoxy-12β, 25-dihydroxy-dommarane-3β-amine (ORA and OSA), a pair of semi-synthetic ocotill...

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Detalles Bibliográficos
Autores principales: Zhang, Yun-Kai, Zhang, Hengyuan, Zhang, Guan-Nan, Wang, Yi-Jun, Kathawala, Rishil J., Si, Rui, Patel, Bhargav A., Xu, Jinyi, Chen, Zhe-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695185/
https://www.ncbi.nlm.nih.gov/pubmed/26296969

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