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Detection of novel and potentially actionable anaplastic lymphoma kinase (ALK) rearrangement in colorectal adenocarcinoma by immunohistochemistry screening

PURPOSE: Anaplastic lymphoma kinase (ALK) rearrangement has been detected in colorectal carcinoma (CRC) using advanced molecular diagnostics tests including exon scanning, fluorescence in situ hybridization (FISH), and next generation sequencing (NGS). We investigated if immunohistochemistry (IHC) c...

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Detalles Bibliográficos
Autores principales: Lee, Jeeyun, Kim, Hee Cheol, Hong, Jung Yong, Wang, Kai, Kim, Sun Young, Jang, Jiryeon, Kim, Seung Tae, Park, Joon Oh, Lim, Ho Yeong, Kang, Won Ki, Park, Young Suk, Lee, Jiyun, Lee, Woo Yong, Park, Yoon Ah, Huh, Jung Wook, Yun, Seong Hyeon, Do, In-Gu, Kim, Seok Hyung, Balasubramanian, Sohail, Stephens, Philip J., Ross, Jeffrey S., Li, Gang Gary, Hornby, Zachary, Ali, Siraj M., Miller, Vincent A., Kim, Kyoung-Mee, Ou, Sai-Hong Ignatius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695188/
https://www.ncbi.nlm.nih.gov/pubmed/26172300