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eIF3 controls cell size independently of S6K1-activity
All multicellular organisms require a life-long regulation of the number and the size of cells, which build up their organs. mTOR acts as a signaling nodule for the regulation of protein synthesis and growth. To activate the translational cascade, mTOR phosphorylates S6 kinase (S6K1), which is liber...
Autores principales: | Schipany, Katharina, Rosner, Margit, Ionce, Loredana, Hengstschläger, Markus, Kovacic, Boris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695191/ https://www.ncbi.nlm.nih.gov/pubmed/26172298 |
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