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Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death

The oncogenic RAS-selective lethal small molecule Erastin triggers a unique iron-dependent form of nonapoptotic cell death termed ferroptosis. Ferroptosis is dependent upon the production of intracellular iron-dependent reactive oxygen species (ROS), but not other metals. However, key regulators rem...

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Detalles Bibliográficos
Autores principales:	Kwon, Min-Young, Park, Eunhee, Lee, Seon-Jin, Chung, Su Wol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695193/ https://www.ncbi.nlm.nih.gov/pubmed/26405158

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