Molecular dynamic simulations of Escherichia colil-asparaginase to illuminate its role in deamination of asparagine and glutamine residues

Acute lymphocytic leukemia (ALL) is an outrageous disease worldwide. l-Asparagine (l-Asn) and l-Glutamine (l-Gln) deamination play a crucial role in ALL treatment. Role of Elspar(®) (l-asparaginase from Escherichia coli) in regulation of l-Asn and l-Gln has been confirmed by the other researchers th...

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Detalles Bibliográficos
Autores principales: Erva, Rajeswara Reddy, Rajulapati, Satish Babu, Potla Durthi, Chandrasai, Bhatia, Mayuri, Pola, Madhuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695448/
https://www.ncbi.nlm.nih.gov/pubmed/28330072
http://dx.doi.org/10.1007/s13205-015-0339-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695448/
https://www.ncbi.nlm.nih.gov/pubmed/28330072
http://dx.doi.org/10.1007/s13205-015-0339-9

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