Cargando…

Downregulation of miR-221 Inhibits Cell Migration and Invasion through Targeting Methyl-CpG Binding Domain Protein 2 in Human Oral Squamous Cell Carcinoma Cells

Oral squamous cell carcinoma (OSCC), the most frequent of all oral cancers, is a type of highly malignant tumors with a high capacity to invade locally and form distant metastases. An increasing number of studies have shown that microRNAs (miRNAs) play an important role in regulating cancer metastas...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Shuqi, Lai, Renfa, Chen, Dan, Yan, Wangxiang, Zhang, Zhaoqiang, Liu, Zhiguo, Ding, Xueqiang, Chen, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695639/ https://www.ncbi.nlm.nih.gov/pubmed/26788506 http://dx.doi.org/10.1155/2015/751672

Ejemplares similares

Oral squamous cell carcinoma (OSCC)-derived exosomal MiR-221 targets and regulates phosphoinositide-3-kinase regulatory subunit 1 (PIK3R1) to promote human umbilical vein endothelial cells migration and tube formation
por: He, Shuqi, et al.
Publicado: (2021)

Functional Downregulation of PD-L1 and PD-L2 by CpG and non-CpG Oligonucleotides in Melanoma Cells
por: Kleemann, Johannes, et al.
Publicado: (2022)

Downregulation of miR-221/222 by a microRNA sponge promotes apoptosis in oral squamous cell carcinoma cells through upregulation of PTEN
por: Zhou, Lijie, et al.
Publicado: (2016)

Oral squamous cell carcinoma cells are resistant to doxorubicin through upregulation of miR-221
por: Du, Liangzhi, et al.
Publicado: (2017)

Expression and clinical significance of methyl-CpG binding domain protein 2 in high-grade serous ovarian cancer
por: Gong, Wangang, et al.
Publicado: (2020)

Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation
por: Wu, Yanyuan, et al.
Publicado: (2010)

Prognostic CpG Methylation Biomarkers Identified by Methylation Array in Esophageal Squamous Cell Carcinoma Patients
por: Kuo, I-Ying, et al.
Publicado: (2014)

Identification of hub methylated‐CpG sites and associated genes in oral squamous cell carcinoma
por: Dai, Yuxin, et al.
Publicado: (2020)

BARX2 expression is downregulated by CpG island hypermethylation and is associated with suppressed cell proliferation and invasion of gastric cancer cells
por: Ma, Juan, et al.
Publicado: (2020)

Preservation of methylated CpG dinucleotides in human CpG islands
por: Panchin, Alexander Y., et al.
Publicado: (2016)

CpG Transformer for imputation of single-cell methylomes
por: De Waele, Gaetan, et al.
Publicado: (2021)

Comparative study of methyl-CpG-binding domain proteins
por: Roloff, Tim C, et al.
Publicado: (2003)

Restoration of CpG Methylation in The Egf Promoter Region during Rat Liver Regeneration
por: Deming, Li, et al.
Publicado: (2015)

MiR-221 Promotes Hepatocellular Carcinoma Cells Migration via Targeting PHF2
por: Fu, Yi, et al.
Publicado: (2019)

Suppressive CpG
por: Van Epps, Heather L.
Publicado: (2005)

Prediction model construction of mouse stem cell pluripotency using CpG and non-CpG DNA methylation markers
por: Joe, Soobok, et al.
Publicado: (2020)

Engineering CpG island DNA methylation in pluripotent cells through synthetic CpG-free ssDNA insertion
por: Tompkins, Joshua, et al.
Publicado: (2023)

CpG oligodeoxyribonucleotide 7909 enhances radiosensitivity via downregulating Oct-4 expression in radioresistant lung cancer cells
por: Xing, Na, et al.
Publicado: (2015)

Seven-CpG-based prognostic signature coupled with gene expression predicts survival of oral squamous cell carcinoma
por: Shen, Sipeng, et al.
Publicado: (2017)

Factors to preserve CpG-rich sequences in methylated CpG islands
por: Miyahara, Hiroki, et al.
Publicado: (2015)

Densely methylated DNA traps Methyl-CpG–binding domain protein 2 but permits free diffusion by Methyl-CpG–binding domain protein 3
por: Leighton, Gage O., et al.
Publicado: (2022)

Single-CpG-resolution methylome analysis identifies clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas
por: Arai, Eri, et al.
Publicado: (2012)

5-Halogenated pyrimidine lesions within a CpG sequence context mimic 5-methylcytosine by enhancing the binding of the methyl-CpG-binding domain of methyl-CpG-binding protein 2 (MeCP2)
por: Valinluck, Victoria, et al.
Publicado: (2005)

Role of miR-132/methyl-CpG-binding protein 2 in the regulation of neural stem cell differentiation
por: Chen, Dong, et al.
Publicado: (2020)

Atorvastatin improves the proliferation and migration of endothelial progenitor cells via the miR-221/VEGFA axis
por: Sun, Lihua, et al.
Publicado: (2020)

The effect of CpG-ODN on antigen presenting cells of the foal
por: Flaminio, M Julia BF, et al.
Publicado: (2007)

Mammalian Non-CpG Methylation: Stem Cells and Beyond
por: Pinney, Sara E.
Publicado: (2014)

An Epigenetic Regulator: Methyl-CpG-Binding Domain Protein 1 (MBD1)
por: Li, Lu, et al.
Publicado: (2015)

CpG stimulation of chronic lymphocytic leukemia cells induces a polarized cell shape and promotes migration in vitro and in vivo
por: Dampmann, Maria, et al.
Publicado: (2020)

In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases
por: Arand, Julia, et al.
Publicado: (2012)

CpG and Non-CpG Methylation in Epigenetic Gene Regulation and Brain Function
por: Jang, Hyun Sik, et al.
Publicado: (2017)

Identification of potential CpG sites for oral squamous cell carcinoma diagnosis via integrated analysis of DNA methylation and gene expression
por: Chen, Le, et al.
Publicado: (2021)

Prediction of CpG-island function: CpG clustering vs. sliding-window methods
por: Hackenberg, Michael, et al.
Publicado: (2010)

CpG Methylation Altered the Stability and Structure of the i-Motifs Located in the CpG Islands
por: Oshikawa, Daiki, et al.
Publicado: (2022)

Recognition of methylated DNA through methyl-CpG binding domain proteins
por: Zou, Xueqing, et al.
Publicado: (2012)

CpG domains downstream of TSSs promote high levels of gene expression
por: Krinner, Simone, et al.
Publicado: (2014)

Methyl CpG binding domain protein 2 (MBD2) in inflammation
por: Lei, Qian, et al.
Publicado: (2022)

Type I Interferon-mediated Stimulation of T Cells by CpG DNA
por: Sun, Siquan, et al.
Publicado: (1998)

Functionally Distinct Subpopulations of CpG-Activated Memory B Cells
por: Henn, Alicia D., et al.
Publicado: (2012)

Effect of CpG ODN on monocytic myeloid derived suppressor cells
por: Shirota, Hidekazu, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_d9233tf9t42p9mmqip88eeq7hr