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Direct Reprogramming of Mouse Fibroblasts to Neural Stem Cells by Small Molecules
Although it is possible to generate neural stem cells (NSC) from somatic cells by reprogramming technologies with transcription factors, clinical utilization of patient-specific NSC for the treatment of human diseases remains elusive. The risk hurdles are associated with viral transduction vectors i...
Autores principales: | Han, Yan-Chuang, Lim, Yoon, Duffieldl, Michael D., Li, Hua, Liu, Jia, Abdul Manaph, Nimshitha Pavathuparambil, Yang, Miao, Keating, Damien J., Zhou, Xin-Fu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695670/ https://www.ncbi.nlm.nih.gov/pubmed/26788068 http://dx.doi.org/10.1155/2016/4304916 |
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